日本語
 Faculty of Medicine / School of Medicine
 Department of Molecular Pathology
 
顔写真 Professor
kuniyasu   hiroki
Repository

Current research field
Human Pathology 
Experimental Pathology 

Research keywords
Gastroentestinal Cancer, Prostate Cancer, Carcinogenesis, Metastasis, Evaluation of Metastatic Potential, Cancer Biology 

Subject of research
癌宿主微小環境に関する研究  増殖因子,サイトカイン,エピジェネティクス  2001- 
大腸癌の転移機構に関する研究  転移関連遺伝子  2000- 
形態学的遺伝子発現プロファイルの転移診断への応用.  組織チップ  2000- 
大腸発がんに影響を与える因子とエピジェネティクス  大腸癌、発がん、エピジェネティクス  2002- 
食物関連発がんにおける宿主ドラマタイプ  大腸癌,口腔癌,タンパク修飾  2004- 
「転移チップ」による転移能診断.     
腸管の形態学的・組織学的再生  壁内神経、自動収縮運動、排便反射、  2005-  腸管の再生を形態的・機能的、さらに、遺伝子発現から検討し、特に、腸管収縮能の再生促進因子を検索し、術後・先天疾患などの治療への応用を目指す

Achievements of joint or funded research
前立腺生検標本を用いた転移能診断      2000-2002       
Evaluation of metastatic Potential of Prostate Cancer Using Nedle Biopsyspecimens      2000-2002       
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Books
The molecular pathology of gastric cancer, In: New Perspectives in Cancer Research and Therapy 2005  2005  Research Signpost         
Molecular pathology of esophageal cancer, In: Gastrointestinal Oncology: Principles and Practices\n  2001  Lippincott, Williams & Wilkins         
Molecular diagnosis to predict the metastatic potential of human prostate cancer, In: Progress in anti-cancer chemotherapy Volume IV\n  2000  Springer-Verlag         
Janus-faced role of linoleic acid in colon cancer  2007  Research Media         
New angiogenic factors in oral cancer  2008  Research Media         
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Papers
Frequent amplification of the c-met gene in scirrhous type stomach cancer    Biochemical and Biophysical Research Communication  Academic Journal    189/ 1, 227-232  1992       
Production of interleukin-15 by human colon cancer cells is\nassociated with induction of mucosal hyperplasia,angiogenesis, and metastasis    Clinical Cancer Reseach  Academic Journal    9/ 13, 4802-4810  2003       
Abenant expression of c-met mRNA in human gastric carcinomas    International Journal of Cancer  Academic Journal    55/ 1, 72-75  1993       
The relative mRNA expression levels of Matrix Metalloproteinase\nto E-cadherin in prostate biopsy specimens distinguishes organ-confined from advanced cancer at radical prostatectomy    Clinical Cancer Research  Academic Journal    9/ 6, 2185-2194  2003       
Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas    International Journal of Cancer  Academic Journal    59/ 5, 597-600  1994       
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